China (Mainland)
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- Product Details
Keywords
- 59277-89-3
- Acyclovir
- C8H11N5O3
Quick Details
- ProName: Acyclovir
- CasNo: 59277-89-3
- Molecular Formula: C8H11N5O3
- Appearance: White crystalline powder
- Application: Antiviral drug substance
- DeliveryTime: 20day
- PackAge: According to the demand of customer
- Port: shanghai
- ProductionCapacity: 20 Metric Ton/Month
- Purity: 98%
- Storage: Sealed, dry, microtherm , avoid light ...
- Transportation: by air or by sea
- LimitNum: 1 Kilogram
- Grade: Industrial Grade,Pharma Grade,Electron...
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Details
| Acyclovir Basic information |
| Product Name: | Acyclovir |
| Synonyms: | 1,9-dihydro-2-amino-9-((2-hydroxyethoxy)methyl)-6h-purin-6-on;2-amino-1,9-dihydro-9-((2-hydroxyethoxy)-methyl)-6h-purin-6-on;aciclovirum(latin);aclovir;Acycolguanosine;bw248u;vipral;virorax |
| CAS: | 59277-89-3 |
| MF: | C8H11N5O3 |
| MW: | 225.2 |
| EINECS: | 261-685-1 |
| Product Categories: | PHARMACEUTICALS;Active Pharmaceutical Ingredients;Purine;Nucleotides and Nucleosides;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Amines;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;API's;Valacyclovir Hydrochloride Monohydrate;Antiviral;Herpes Viruses;Anti-virals;THALOMID;inhibitor |
| Mol File: | 59277-89-3.mol |
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| Acyclovir Chemical Properties |
| Melting point | 256-257°C |
| Boiling point | 366.71°C (rough estimate) |
| density | 1.3654 (rough estimate) |
| refractive index | 1.8000 (estimate) |
| storage temp. | −20°C |
| solubility | H2O: 0.7 mg/mL |
| form | powder |
| color | white |
| Water Solubility | Soluble in 1M HCl at 50mg/ml. Soluble in water at 0.7mg/ml. Also soluble in DMSO |
| Merck | 14,146 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 59277-89-3(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 36/37/38-40-20/21/22 |
| Safety Statements | 22-24/25-36-26-23 |
| WGK Germany | 2 |
| RTECS | UP0791400 |
| HazardClass | IRRITANT |
| Hazardous Substances Data | 59277-89-3(Hazardous Substances Data) |
| Toxicity | LD50 in mice (mg/kg): >10,000 orally; 1000 i.p. (Schaeffer) |
| Acyclovir Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder |
| Uses | hypnotic |
| Uses | Orally active acyclic nucleoside with inhibitory activity towards several herpes viruses. Antiviral |
| Definition | ChEBI: An oxopurine that is guanine substituted by a (2-hydroxyethoxy)methyl substituent at position 9. |
| Biological Activity | Antiviral agent, active against herpes simplex viruses HSV-1 and HSV-2 (EC 50 values are 0.85 and 0.86 μ M respectively). Interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate. Induces apoptosis in cells transfected with HSV-TK (suicidal gene therapy). |
| Acyclovir Preparation Products And Raw materials |