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Home > Products >  110078-46-1PLERIXAFORPLERIXAFOR

110078-46-1PLERIXAFORPLERIXAFOR CAS NO.110078-46-1

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,
  • Product Details

Keywords

  • 110078-46-1
  • PLERIXAFOR
  • C28H54N8

Quick Details

  • ProName: 110078-46-1PLERIXAFORPLERIXAFOR
  • CasNo: 110078-46-1
  • Molecular Formula: C28H54N8
  • Appearance: White or off-white Solid
  • Application: intermediate
  • DeliveryTime: 20day
  • PackAge: According to the demand of customer
  • Port: shanghai
  • ProductionCapacity: 20 Metric Ton/Day
  • Purity: 99.0%
  • Storage: Sealed, dry, microtherm , avoid light ...
  • Transportation: According to the demand of customer
  • LimitNum: 1 Kilogram
  • Grade: Industrial Grade,Pharma Grade,Electron...

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Details

PLERIXAFOR Basic information
Product Name: PLERIXAFOR
Synonyms: PLERIXAFOR;1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane;1,4,8,11-Tetraazacyclotetradecane, 1,1'-(1,4-phenylenebis(methylene))bis-;Mozobil;Sdz sid 791;Unii-S915p5499n;1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane;Plerixafor(AMD3100)
CAS: 110078-46-1
MF: C28H54N8
MW: 502.791
EINECS:  
Product Categories: Aromatics;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 110078-46-1.mol
PLERIXAFOR Structure
 
PLERIXAFOR Chemical Properties
mp  122-125°C
density  0.962
storage temp.  Refrigerator
 
Safety Information
MSDS Information
 
 
PLERIXAFOR Usage And Synthesis
Chemical Properties White Solid
Usage Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively
Usage Plerixafor is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in p atients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM).

 

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