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Acarbose Basic information |
Product Name: |
Acarbose |
Synonyms: |
O-4,6-DIDEOXY-4-[[[1S-(1A,4A,5BETA,6A)]-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-2-CYCLOHEXEN-1-YL]AMINO]-ALPHA-D-GLUCOPYRANOSYL-(1-4)-O-ALPHA-D-GLUCOPYRANOSYL-(1-4)-D-GLUCOSE;-alpha-d-glucopyranosyl-(1-4)-;bay-g5421;d-glucose,o-4,6-dideoxy-4-(((1s-(1-alpha,4-alpha,5-beta,6-alpha))-4,5,6-trihyd;roxy-3-(hydroxymethyl)-2-cyclohexen-1-yl)amino)-alpha-d-glucopyranosyl-(1-4)-o;ACARBOSE;5-[5-[3,4-DIHYDROXY-6-METHYL-5-[[4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)-1-CYCLOHEX-2-ENYL]AMINO]OXAN-2-YL]OXY-3,4-DIHYDROXY-6-(HYDROXYMETHYL)OXAN-2-YL]OXY-6-(HYDROXYMETHYL)OXANE-2,3,4-TRIOL;Glucobay |
CAS: |
56180-94-0 |
MF: |
C25H43NO18 |
MW: |
645.6 |
EINECS: |
260-030-7 |
Product Categories: |
Sugars, Carbohydrates & Glucosides;Intermediates & Fine Chemicals;Oligosaccharides;Pharmaceuticals;API's;API;SEROQUEL |
Mol File: |
56180-94-0.mol |
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Acarbose Chemical Properties |
Melting point |
165-170°C |
storage temp. |
Store at RT |
Merck |
14,18 |
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Acarbose Usage And Synthesis |
Chemical Properties |
Off-White Solid |
Usage |
Used as an anitdiabetic |
Usage |
Used as an anti-diabetic. |
Usage |
alpha-glucosidase & saccharase inhibitor, antidiabetes, antihyperlipidaemia, antiobesity |
Usage |
antipsychotic: 5HT antagonist, dopamine antagonist, H1-antihistamine, alpha adrenergic blocker |
Usage |
Acarbose is pseudo-oligosaccharide with a terminal C7-cyclitol patented in 1975 by Bayer. Acarbose is a component of the amylostatin complex produced by a species of Actinoplanes and Streptomyces. Acarbose acts as a potent inhibitor of alpha-glucosidases and saccharases. Since 1990, acarbose has been used therapeutically for the treatment of type 2 diabetes. |
Usage |
b-glucosidase inhibitor, antidiabetic |
Usage |
Acarbose is pseudo-oligosaccharide with a terminal C7-cyclitol patented in 1975 by Bayer. Acarbose is a component of the amylostatin complex produced by species of Actinoplanes and Streptomyces. Acarbose acts as a potent inhibitor of α-glucosidases and saccharases. Since 1990, acarbose has been used therapeutically for the treatment of type 2 diabetes. |
Definition |
ChEBI: A tetrasaccharide derivative consisting of a dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl C7 cyclitol moiety [called valienol (or valienamine)] linked via nitrogen to isomaltotriose. |
Biological Activity |
Inhibitor of intestinal α -glucosidase (IC 50 = 11 nM). Antidiabetic; inhibits the hydrolysis of complex carbohydrates. |
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Acarbose Preparation Products And Raw materials |